Dimethylglyoxime
Dimethylglyoxime (Biacetyl dioxime) belongs to the class of oximes and consists of two acetyl groups attached to a nitrogen atom, which in turn is attached to another nitrogen atom through a diimine bond. Dimethylglyoxime is a specific chelator of Ni that inhibits or slows the aggregation of Aβ peptides in vitro[1].
Product Specifications
CAS Number
[95-45-4]
Product Name Alternative
Biacetyl dioxime
UNSPSC
12352200
Hazard Statement
H228
Target
Biochemical Assay Reagents
Type
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/biacetyl-dioxime.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(/C(C)=N/O)=N\O
Molecular Formula
C4H8N2O2
Molecular Weight
116.12
Precautions
H228
References & Citations
[1]Benoit SL, et al. The nickel-chelator dimethylglyoxime inhibits human amyloid beta peptide in vitro aggregation. Sci Rep. 2021 Mar 23;11 (1) :6622. |[2]Benoit SL, et al. The nickel-chelator dimethylglyoxime inhibits human amyloid beta peptide in vitro aggregation. Sci Rep. 2021 Mar 23;11 (1) :6622.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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