Big Gastrin (Human, Highly Pure)

<strong>Big Gastrin (Human, Highly Pure)</strong>_x000D_ _x000D_ <b>Price per 0.1 mg: </b>$495_x000D_ <b>Catalog number: </b>MDP0567_x000D_ <b>Name:</b> Pyr-Leu-Gly-Pro-Gln-Gly-Pro-Pro-His-Leu-Val-Ala-Asp-Pro-Ser-Lys-Lys-Gln-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2_x000D_ <b>Other name(s): </b>Big Gastrin (Human)_x000D_ <b>Molecular Formula: </b>C₁₇₆H₂₅₁N₄₃O₅₃S_x000D_ <b>Molecular Mass: </b>3849.2_x000D_ <b>CAS #: </b>60675-77-6_x000D_ <b>Storage Temperature: </b>-20¬∞C_x000D_ _x000D_ <b>Indication for Use:</b>_x000D_ This product if for Research Use Only (RUO). This product is not for administration to humans or animals. This product is not for human or veterinary diagnostic or therapeutic use._x000D_ _x000D_ <a href="https://moleculardepot.com/wp-content/uploads/2020/06/MDP0567-SDS.pdf"><strong>MSDS</strong></a>_x000D_ _x000D_ <b>About Big-Gastrin</b>_x000D_ _x000D_ Big gastrin (also known as G-34) is a peptide portion of gastrin containing 34 amino acids. It acts as a hormone produced by G cells of the stomach. G-34 has been shown to promote the secretion of gastric acid in certain species. Research has shown that extracts of antral mucosa contained large amounts of a peptide similar to the amino-terminal fragment of G34._x000D_ _x000D_ <strong>References</strong>_x000D_ <ul>_x000D_ <li>Effect of antrectomy and drug-induced achlorhydria on urinary excretion of N-terminal biggastrin immunoreactivity in rats.</li>_x000D_ <li class="labs-docsum-citation full-citation"><span class="labs-docsum-authors full-authors">Miyazaki Y, Shinomura Y, Yasunaga Y, Higashimoto Y, Kanayama S, Aoki T, Okuda Y, Narita T, Miwa K, Miyazaki I, et al.</span> <span class="labs-docsum-journal-citation full-journal-citation">Regul Pept. 1993 Nov 19;49(1):49-56.</span></li>_x000D_ <li>Immunohistochemical examination of precursors, and g/CCK-2 receptor in human esophageal squamous cell carcinomas._x000D_ <div class="labs-docsum-citation full-citation"><span class="labs-docsum-authors full-authors">Yuan A, Liu J, Liu Y, Bj√∏rnsen T, Varro A, Cui G.</span> <span class="labs-docsum-journal-citation full-journal-citation">Pathol Oncol Res. 2008 Dec;14(4):449-55.</span></div></li>_x000D_ <li>Sulfated stimulates ghrelin and growth hormone release but inhibits insulin secretion in cattle._x000D_ <div class="labs-docsum-citation full-citation"><span class="labs-docsum-authors full-authors">Zhao H, Yannaing S, Thanthan S, Kuwayama H.</span> <span class="labs-docsum-journal-citation full-journal-citation">Peptides. 2011 Nov;32(11):2218-24.</span></div></li>_x000D_ <li>Expression of gastrin, gastrin/CCK-B and gastrin/CCK-C receptors in human colorectal carcinomas._x000D_ <div class="labs-docsum-citation full-citation"><span class="labs-docsum-authors full-authors">Imdahl A, Mantamadiotis T, Eggstein S, Farthmann EH, Baldwin GS.</span> <span class="labs-docsum-journal-citation full-journal-citation">J Cancer Res Clin Oncol. 1995;121(11):661-6. </span></div></li>_x000D_ <li>Comparison of biological activity and disappearance rates of synthetic bg, little gastrin and minigastrin in the dog._x000D_ <div class="labs-docsum-citation full-citation"><span class="labs-docsum-authors full-authors">Konturek SJ, Tasler J, Mikos E, Jaeger E, W√ºnsch E.</span> <span class="labs-docsum-journal-citation full-journal-citation">Hepatogastroenterology. 1980 Feb;27(1):35-40.</span></div></li>_x000D_ <li>Interaction of synthetic human gastrin with blood proteins of man and animals._x000D_ <div class="labs-docsum-citation full-citation"><span class="labs-docsum-authors full-authors">Polosatov MV, Klimov PK, Masevich CG, Samartsev MA, W√ºnsch E.</span> <span class="labs-docsum-journal-citation full-journal-citation"><a href="https://pubmed.ncbi.nlm.nih.gov/463490/">Acta Hepatogastroenterol (Stuttg)</a>. 1979 Apr;26(2):154-9.</span></div>_x000D_ <b>¬†</b></li>_x000D_ </ul>