Arterolane (maleate)
Product Specifications
UNSPSC Description
Arterolane (OZ 277) (maleate) is an orally active antimalarial. Arterolane exhibits potent activity against erythrocytic stages of P. falciparum and Plasmodium vivax. Arterolane (maleate) is promising for research of falciparum malaria[1][2].
Target Antigen
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/arterolane-maleate.html
Smiles
O=C(NCC(N)(C)C)C[C@H](CC1)CC[C@]21OO[C@]3(O2)[C@H]4C[C@@H]5C[C@H](C4)C[C@H]3C5.O=C(O)/C=C\C(O)=O
Molecular Weight
508.60
References & Citations
[1]Toure OA, et al. A Phase 3, Double-Blind, Randomized Study of Arterolane Maleate-Piperaquine Phosphate vs Artemether-Lumefantrine for Falciparum Malaria in Adolescent and Adult Patients in Asia and Africa. Clin Infect Dis. 2016 Apr 15;62(8):964-971. |[2]Toure OA, et al. Efficacy and safety of fixed dose combination of arterolane maleate and piperaquine phosphate dispersible tablets in paediatric patients with acute uncomplicated Plasmodium falciparum malaria: a phase II, multicentric, open-label study. Malar J. 2015 Nov 25;14:469.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-10852A/Arterolane-maleate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10852A/
Clinical Information
Phase 3
CAS Number
959520-73-1
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