BDC2.5 mimotope 1040-31

BDC2.5 mimotope 1040-31, a BDC2.5 TCR reactive peptide, is a strong agonistic peptide for diabetogenic T cell clone BDC2.5, and the 1040-31 peptide is specific for BDC 2.5 TCR Tg+ T cells[1][2].

Product Specifications

CAS Number

[329696-49-3]

UNSPSC

12352209

Target

Transmembrane Glycoprotein

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/bdc2-5-mimotope-1040-31.html

Purity

98.00

Solubility

10 mM in DMSO

Smiles

O=C(O)CC[C@@H](C(O)=O)NC([C@H](CCSC)NC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@H](CC1=CNC2=CC=CC=C12)NC([C@H](CC(C)C)NC([C@H]3N(C([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@H](CC4=CC=C(C=C4)O)N)=O)=O)=O)CCC3)=O)=O)=O)=O)=O)=O

Molecular Formula

C63H97N17O14S

Molecular Weight

1348.61

References & Citations

[1]Dai YD, et al. A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas. J Immunol. 2005 Sep 15;175 (6) :3621-7.|[2]Masteller EL, et al. Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice. J Immunol. 2005 Sep 1;175 (5) :3053-9.