Policresulen
Product Specifications
UNSPSC Description
Policresulen is a potent inhibitor of DENV2 NS2B/NS3 protease (IC50 of 0.48 μg/mL). Policresulen inhibits DENV2 replication in BHK-21 cells with IC50 of 4.99 μg/mL. Policresulen acts as a competitive inhibitor of the protease, and slightly affects the protease stability[1].
Target Antigen
Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/policresulen.html
Solubility
DMSO : 50 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Smiles
CC1=C(C)C(O)=C(S(=O)(O)=O)C=C1CC.[n]
References & Citations
[1]Wu DW, et al. Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells. Acta Pharmacol Sin. 2015;36(9):1126-1136.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W129596/Policresulen-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W129596/Policresulen-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
101418-00-2
Available Sizes
Curated Selection
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