TYVPANASL (TFA)
TYVPANASL TFA is a MHC I-binding CD8 T cell epitope of nine amino acids from HER2/neu. TYVPANASL TFA can be used to prepare J-LEAPS vaccine[1].
Product Specifications
UNSPSC
12352209
Target
EGFR; MHC
Type
Peptides
Related Pathways
Immunology/Inflammation; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tyvpanasl-tfa.html
Solubility
10 mM in DMSO
Smiles
OC(C=C1)=CC=C1C[C@H](NC([C@@H](N)[C@H](O)C)=O)C(N[C@@H](C(C)C)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O.O=C(C(F)(F)F)O.[x]
Molecular Formula
C42H66N10O14.xC2HF3O2
Molecular Weight
935.03 (free acid)
References & Citations
[1]Ken S Rosenthal, et al. LEAPS Vaccine Incorporating HER-2/neu Epitope Elicits Protection That Prevents and Limits Tumor Growth and Spread of Breast Cancer in a Mouse Model. J Immunol Res. 2017;2017:3613505.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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