PMEDAP
PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP has anti-murine cytomegalovirus (MCMV) activity. PMEDAP is a very potent inhibitor of Moloney murine sarcoma virus (MSV) -induced tumor formation and associated mortality[1][2].
Product Specifications
CAS Number
113852-41-8
UNSPSC
12352005
Target
CMV; HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/pmedap.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=P(O)(COCCN1C=NC2=C1N=C(N)N=C2N)O
Molecular Formula
C8H13N6O4P
Molecular Weight
288.20
References & Citations
[1]Neyts J, et al. Activity of the anti-HIV agent 9- (2-phosphonyl-methoxyethyl) -2,6-diaminopurine against cytomegalovirus in vitro and in vivo [published correction appears in Eur J Clin Microbiol Infect Dis 1993 Jul;12 (7) :following 477]. Eur J Clin Microbiol Infect Dis. 1993;12 (6) :437-446. |[2]Naesens L, et al. 9- (2-Phosphonylmethoxyethyl) -2,6-diaminopurine (PMEDAP) : a novel agent with anti-human immunodeficiency virus activity in vitro and potent anti-Moloney murine sarcoma virus activity in vivo. Eur J Clin Microbiol Infect Dis. 1989;8 (12) :1043-1047.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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