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Neuropeptide SF (mouse, rat) (TFA)

Neuropeptide SF (mouse, rat) TFA is a potent neuropeptide FF receptor agonist with Ki values are 48.4 nM and 12.1 nM for NPFF1 and NPFF2, respectively. Neuropeptide SF TFA increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) [1].

Product Specifications

UNSPSC

12352209

Target

Neuropeptide Y Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/neuropeptide-sf-mouse-rat-tfa.html

Solubility

10 mM in DMSO

Smiles

O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H]2N(C([C@H](C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CO)N)=O)=O)=O)=O)CCC2)=O)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C42H66F3N13O12

Molecular Weight

1002.05

References & Citations

[1]Miklós Jászberényi, et al. The actions of neuropeptide SF on the hypothalamic-pituitary-adrenal axis and behavior in rats.Regul Pept. 2014 Jan 10;188:46-51.|[2]K Jhamandas, et al. Facilitation of spinal morphine analgesia in normal and morphine tolerant animals by neuropeptide SF and related peptides.Peptides. 2006 May;27 (5) :953-63.|[3]C Gouardères, et al. Quantitative autoradiographic distribution of NPFF1 neuropeptide FF receptor in the rat brain and comparison with NPFF2 receptor by using [125I]YVP and [ (125I]EYF as selective radioligands. Neuroscience. 2002;115 (2) :349-61.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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