Neuropeptide SF (mouse, rat) (TFA)
Neuropeptide SF (mouse, rat) TFA is a potent neuropeptide FF receptor agonist with Ki values are 48.4 nM and 12.1 nM for NPFF1 and NPFF2, respectively. Neuropeptide SF TFA increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) [1].
Product Specifications
UNSPSC
12352209
Target
Neuropeptide Y Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/neuropeptide-sf-mouse-rat-tfa.html
Solubility
10 mM in DMSO
Smiles
O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H]2N(C([C@H](C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CO)N)=O)=O)=O)=O)CCC2)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C42H66F3N13O12
Molecular Weight
1002.05
References & Citations
[1]Miklós Jászberényi, et al. The actions of neuropeptide SF on the hypothalamic-pituitary-adrenal axis and behavior in rats.Regul Pept. 2014 Jan 10;188:46-51.|[2]K Jhamandas, et al. Facilitation of spinal morphine analgesia in normal and morphine tolerant animals by neuropeptide SF and related peptides.Peptides. 2006 May;27 (5) :953-63.|[3]C Gouardères, et al. Quantitative autoradiographic distribution of NPFF1 neuropeptide FF receptor in the rat brain and comparison with NPFF2 receptor by using [125I]YVP and [ (125I]EYF as selective radioligands. Neuroscience. 2002;115 (2) :349-61.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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