Human FGF-14 (Fibroblast Growth Factor-14)

<strong>Human FGF-14 (Fibroblast Growth Factor-14)</strong>_x000D_ <strong>Catalog number:</strong> B2018686_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> ~27 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> FGF14, Fibroblast Growth Factor 14_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Perlman S. Hereditary Ataxia Overview 1998 Oct 28 [updated 2024 Sep 12]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(®) [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024._x000D_ 2: Pellerin D, Danzi MC, Wilke C, Renaud M, Fazal S, Dicaire MJ, Scriba CK, Ashton C, Yanick C, Beijer D, Rebelo A, Rocca C, Jaunmuktane Z, Sonnen JA, Larivière R, Genís D, Molina Porcel L, Choquet K, Sakalla R, Provost S, Robertson R, Allard-Chamard X, Tétreault M, Reiling SJ, Nagy S, Nishadham V, Purushottam M, Vengalil S, Bardhan M, Nalini A, Chen Z, Mathieu J, Massie R, Chalk CH, Lafontaine AL, Evoy F, Rioux MF, Ragoussis J, Boycott KM, Dubé MP, Duquette A, Houlden H, Ravenscroft G, Laing NG, Lamont PJ, Saporta MA, Schüle R, Schöls L, La Piana R, Synofzik M, Zuchner S, Brais B. Deep Intronic FGF14 GAA Repeat Expansion in Late-Onset Cerebellar Ataxia N Engl J Med. 2023 Jan 12;388(2):128-141._x000D_ 3: Pellerin D, Danzi MC, Renaud M, Houlden H, Synofzik M, Zuchner S, Brais B. Spinocerebellar ataxia 27B: A novel, frequent and potentially treatable ataxia Clin Transl Med. 2024 Jan;14(1):e1504._x000D_ 4: Pellerin D, Danzi M, Renaud M, Houlden H, Synofzik M, Zuchner S, Brais B. GAA-FGF14-Related Ataxia 2024 Jan 25. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(®) [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024._x000D_ 5: Rafehi H, Read J, Szmulewicz DJ, Davies KC, Snell P, Fearnley LG, Scott L, Thomsen M, Gillies G, Pope K, Bennett MF, Munro JE, Ngo KJ, Chen L, Wallis MJ, Butler EG, Kumar KR, Wu KH, Tomlinson SE, Tisch S, Malhotra A, Lee-Archer M, Dolzhenko E, Eberle MA, Roberts LJ, Fogel BL, Brüggemann N, Lohmann K, Delatycki MB, Bahlo M, Lockhart PJ. An intronic GAA repeat expansion in FGF14 causes the autosomal-dominant adult-onset ataxia SCA50/ATX-FGF14 Am J Hum Genet. 2023 Jan 5;110(1):105-119._x000D_ 6: Di Re J, Wadsworth PA, Laezza F. Intracellular Fibroblast Growth Factor 14: Emerging Risk Factor for Brain Disorders Front Cell Neurosci. 2017 Apr 19;11:103._x000D_ 7: Wilke C, Pellerin D, Mengel D, Traschütz A, Danzi MC, Dicaire MJ, Neumann M, Lerche H, Bender B, Houlden H; RFC1 study group; Züchner S, Schöls L, Brais B, Synofzik M. GAA-FGF14 ataxia (SCA27B): phenotypic profile, natural history progression and 4-aminopyridine treatment response Brain. 2023 Oct 3;146(10):4144-4157._x000D_ 8: Turkowski K, Herzberg F, Günther S, Brunn D, Weigert A, Meister M, Muley T, Kriegsmann M, Schneider MA, Winter H, Thomas M, Grimminger F, Seeger W, Savai Pullamsetti S, Savai R. Fibroblast Growth Factor-14 Acts as Tumor Suppressor in Lung Adenocarcinomas Cells. 2020 Jul 22;9(8):1755._x000D_ 9: Graves TD, Snell HD, Khodakhah K, Griggs RC, Jen JC. The episodic ataxias Handb Clin Neurol. 2024;203:123-133._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34597335">10: Tezuka Y, Eguchi-Ishimae M, Ozaki E, Ito T, Ishii E, Eguchi M. Activation of fibroblast growth factor-inducible 14 in the early phase of childhood IgA nephropathy PLoS One. 2021 Oct 1;16(10):e0258090. </a>_x000D_ _x000D_ <strong>Products Related to Human FGF-14 (Fibroblast Growth Factor-14) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>