Nazartinib S-enantiomer
Nazartinib S-enantiomer (EGF816 S-enantiomer) is the less active S-enantiomer of Nazartinib. Nazartinib (EGF816) is an EGFR inhibitor.
Product Specifications
CAS Number
[1508256-20-9]
Product Name Alternative
EGF816 (S-enantiomer)
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/EGF816-S-enantiomer.html
Concentration
10mM
Purity
98.66
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C)=NC=C1)NC2=NC3=CC=CC(Cl)=C3N2[C@@H]4CN(C(/C=C/CN(C)C)=O)CCCC4
Molecular Formula
C26H31ClN6O2
Molecular Weight
495.02
References & Citations
[1]Gerald Lelais, et al. Compounds and compositions for modulating egfr activity. WO 2013184757A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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