Rho Kinase Inhibitor

<strong>Rho Kinase Inhibitor</strong>_x000D_ <strong>Catalog number:</strong> B2014010_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 392.3 g/mol_x000D_ <strong>Supplied as:</strong> Solid_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Rho Kinase Inhibitor, H-1152, H-1152P, (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine, 2HCl, ROCK Inhibitor, Dimethylfasudil (diMF, H-1152P)_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wang T, Kang W, Du L, Ge S. Rho-kinase inhibitor Y-27632 facilitates the proliferation, migration and pluripotency of human periodontal ligament stem cells J Cell Mol Med. 2017 Nov;21(11):3100-3112._x000D_ 2: Shimokawa H, Sunamura S, Satoh K. RhoA/Rho-Kinase in the Cardiovascular System Circ Res. 2016 Jan 22;118(2):352-66._x000D_ 3: Abedi F, Hayes AW, Reiter R, Karimi G. Acute lung injury: The therapeutic role of Rho kinase inhibitors Pharmacol Res. 2020 May;155:104736._x000D_ 4: Zhang Y, Wang X, Jiang C, Chen Z, Ni S, Fan H, Wang Z, Tian F, An J, Yang H, Hao D. Rho Kinase Inhibitor Y27632 Improves Recovery After Spinal Cord Injury by Shifting Astrocyte Phenotype and Morphology via the ROCK/NF-B/C3 Pathway Neurochem Res. 2022 Dec;47(12):3733-3744._x000D_ 5: Srikawnawan W, Songsaad A, Gonmanee T, Thonabulsombat C, Phruksaniyom C, White KL, Ruangsawasdi N. Rho kinase_inhibitor induced human dental pulp stem cells to differentiate into neurons Life Sci. 2022 Jul 1;300:120566._x000D_ 6: Syed ZA, Rapuano CJ. Rho kinase (ROCK) inhibitors in the management of corneal endothelial disease Curr Opin Ophthalmol. 2021 May 1;32(3):268-274._x000D_ 7: Fukumoto Y, Shimokawa H. Rho-kinase_inhibitors Handb Exp Pharmacol. 2013;218:351-63._x000D_ 8: Zhang W, Li X, Zhang Y. Rho-kinase_inhibitor attenuates airway mucus hypersecretion and inflammation partly by downregulation of IL-13 and the JNK1/2-AP1 signaling pathway Biochem Biophys Res Commun. 2019 Aug 20;516(2):571-577._x000D_ 9: Satoh S, Ikegaki I, Kawasaki K, Asano T, Shibuya M. Pleiotropic effects of the rho-kinase_inhibitor fasudil after subarachnoid hemorrhage: a review of preclinical and clinical studies Curr Vasc Pharmacol. 2014;12(5):758-65._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25925979">10: Odagiri K, Watanabe H. Effects of the Rho-kinase inhibitor, fasudil, on pulmonary hypertension Circ J. 2015;79(6):1213-4. </a>_x000D_ _x000D_ <strong>Products Related to Rho Kinase Inhibitor can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>