EP300/CBP ligand 1
Product Specifications
UNSPSC Description
EP300/CBP ligand 1 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). EP300/CBP ligand 1 can be used for synthesis dCE-2 (HY-161958)[1].
Target Antigen
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/ep300-cbp-ligand-1.html
Smiles
CN(C=C1)N=C1C2=CC(C(NC3=CC=CC4=C3C=C(C)N=N4)=O)=CC(NC(C)=O)=C2
Molecular Weight
400.43
References & Citations
[1]Cheng-Sánchez I, et al. Structure-Based Design of CBP/EP300 Degraders: When Cooperativity Overcomes Affinity. JACS Au. 2024 Aug 8;4(9):3466-3474.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161959/EP300-CBP-ligand-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161959/
Clinical Information
No Development Reported
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