EP300/CBP ligand 1
EP300/CBP ligand 1 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) . EP300/CBP ligand 1 can be used for synthesis dCE-2 (HY-161958) [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ep300-cbp-ligand-1.html
Smiles
CN(C=C1)N=C1C2=CC(C(NC3=CC=CC4=C3C=C(C)N=N4)=O)=CC(NC(C)=O)=C2
Molecular Formula
C22H20N6O2
Molecular Weight
400.43
References & Citations
[1]Cheng-Sánchez I, et al. Structure-Based Design of CBP/EP300 Degraders: When Cooperativity Overcomes Affinity. JACS Au. 2024 Aug 8;4 (9) :3466-3474.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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