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EP300/CBP ligand 1

EP300/CBP ligand 1 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) . EP300/CBP ligand 1 can be used for synthesis dCE-2 (HY-161958) [1].

Product Specifications

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ep300-cbp-ligand-1.html

Smiles

CN(C=C1)N=C1C2=CC(C(NC3=CC=CC4=C3C=C(C)N=N4)=O)=CC(NC(C)=O)=C2

Molecular Formula

C22H20N6O2

Molecular Weight

400.43

References & Citations

[1]Cheng-Sánchez I, et al. Structure-Based Design of CBP/EP300 Degraders: When Cooperativity Overcomes Affinity. JACS Au. 2024 Aug 8;4 (9) :3466-3474.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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