HSP90-IN-30
Product Specifications
UNSPSC Description
HSP90-IN-30 (compound 3e) inhibits HSP90 chaperone activity. HSP90-IN-30 inhibits the activity of HIF-1 transcriptional under hypoxia with an IC50 value of 2.16 μM[1].
Target Antigen
HIF/HIF Prolyl-Hydroxylase; HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hsp90-in-30.html
Solubility
10 mM in DMSO
Smiles
CC(C)CC(CC[BH]1234[B]567(C8=C(C(NC(C)C)=O)N(CC9=CC=CC=C9)N=N8)[BH]1%10%11[BH]5%12%13[BH]6%14%15[BH]72%16[BH]%14%17%18[BH]%15%12%19[BH]%10%13%20[BH]%113%21[BH]%164%17[BH]%20%21%19%18)=O
Molecular Weight
497.28
References & Citations
[1]Yujie Shao, et al. Discovery of Disubstituted Carboranes as Inhibitors of Heat Shock Protein 90–Heat Shock Factor 1 Interaction. ACS Med. Chem. Lett. 2024.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161427/HSP90-IN-30-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161427/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1040067-01 0.02 mg (E-Coli)
Recombinant Mycobacterium gilvum Elongation factor P (efp)
Ask
View Details MBS1040067-02 0.1 mg (E-Coli)
Recombinant Mycobacterium gilvum Elongation factor P (efp)
Ask
View Details 
MBS1040067-03 0.02 mg (Yeast)
Recombinant Mycobacterium gilvum Elongation factor P (efp)
Ask
View Details 
MBS1040067-04 0.1 mg (Yeast)
Recombinant Mycobacterium gilvum Elongation factor P (efp)
Ask
View Details MBS1040067-05 0.02 mg (Baculovirus)
Recombinant Mycobacterium gilvum Elongation factor P (efp)
Ask
View Details