HDAC-IN-81
HDAC-IN-81 (Compound 11g) is an HDAC inhibitor that can effectively inhibit HDAC1 (IC50 = 4.5 nM) . HDAC-IN-81 possesses anti-cancer cell proliferation activity and can induce cell apoptosis[1].
Product Specifications
CAS Number
2787560-44-3
UNSPSC
12352005
Target
Apoptosis; HDAC
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-81.html
Smiles
CC(N(CC1)CC2=C1C3=CC=CC=C3N2CCCCCCC(NO)=O)=O
Molecular Formula
C20H27N3O3
Molecular Weight
357.45
References & Citations
[1]Fan S, et al. Design and optimization of novel Tetrahydro-β-carboline-based HDAC inhibitors with potent activities against tumor cell growth and metastasis[J]. Bioorganic & Medicinal Chemistry Letters, 2024: 129986.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1
Frequently Asked Questions
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