Sp-8-Br-cGMPS
Product Specifications
UNSPSC Description
Sp-8-Br-cGMPS is an analog of cGMP. Sp-8-Br-cGMPS is an agonist for cGMP-gated cation channels (CNG channels), with an EC50 of 106.5 μM. Sp-8-Br-cGMPS induces the currents, without the ability to stabilize the channel open state as a full agonist[1].
Target Antigen
HCN Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sp-8-br-cgmps.html
Smiles
O=C(NC(N)=N1)C2=C1N(C(Br)=N2)[C@H]3[C@H](O)[C@H](O[P@@]4(S)=O)[C@@H](CO4)O3
Molecular Weight
440.17
References & Citations
[1]Wei JY, et al., Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J Mol Neurosci. 1998 Feb;10(1):53-64.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-137639/Sp-8-Br-cGMPS-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-137639/
Clinical Information
No Development Reported
CAS Number
153660-03-8
Curated Selection
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