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IL-20R alpha, Human (HEK293, Fc)

Selected Variant

HY-P77419

Size: 1 Each

IL-20R alpha Protein (IL20RA) is the alpha subunit of IL-20 receptor, forms functional heterodimers with different subunit protein and involves in STAT3 activation pathway[1]. The IL20RA/IL20RB dimer is a receptor for IL-19, IL-20 and IL-24, while the IL20RA/IL10RB dimer is a receptor for IL-26[3]. IL-20R alpha Protein is consists of 553 amino acids (M1-N553) with a transmembrane domain (251-271 a.a.) . IL-20R alpha Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal hFc-tag.

Product Specifications

Product Name Alternative

IL-20R alpha Protein, Human (HEK293, Fc), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-20r-alpha-protein-human-hek293-fc.html

Molecular Formula

53832 (Gene_ID) Q9UHF4-1 (V30-K250) (Accession)

Molecular Weight

Approximately 52 kDa.

References & Citations

[1]Wang F, et al. Prominent production of IL-20 by CD68+/CD11c+ myeloid-derived cells in psoriasis: Gene regulation and cellular effects. J Invest Dermatol. 2006 Jul;126 (7) :1590-9.|[2]Blumberg H, et al. Interleukin 20: discovery, receptor identification, and role in epidermal function. Cell. 2001 Jan 12;104 (1) :9-19.|[3]Sheikh F, et al. Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2. J Immunol. 2004 Feb 15;172 (4) :2006-10.|[4]Wang F, et al. Prominent production of IL-20 by CD68+/CD11c+ myeloid-derived cells in psoriasis: Gene regulation and cellular effects. J Invest Dermatol. 2006 Jul;126 (7) :1590-9.

Shipping Conditions

Dry ice.

Scientific Category

Recombinant Proteins

Price

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