Peucedanol
Peucedanol is a non-competitive inhibitor of CYP3A4 with a Ki value of 4.07 μM and a competitive inhibitor of CYP1A2 and CYP2D6 with Ki values of 3.39 μM and 6.77 μM, respectively[1].
Product Specifications
CAS Number
46992-81-8
UNSPSC
12352005
Target
Cytochrome P450
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/peucedanol.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2=C(C=C1)C=C(CC(C(C)(C)O)O)C(O)=C2
Molecular Formula
C14H16O5
Molecular Weight
264.27
References & Citations
[1]Cun Zhang, et al. In vitro study on the effect of peucedanol on the activity of cytochrome P450 enzymes. Pharm Biol. 2021 Dec;59 (1) :935-940.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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