Curcumin-β-D-glucuronide
Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer[1][2].
Product Specifications
CAS Number
227466-72-0
UNSPSC
12352005
Hazard Statement
H302+H312+H332, H315, H319, H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/curcumin-β-d-glucuronide.html
Purity
98.01
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC(C=C(C=C1)/C=C/C(CC(/C=C/C2=CC(OC)=C(C=C2)O)=O)=O)=C1O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O)=O
Molecular Formula
C27H28O12
Molecular Weight
544.50
Precautions
H302+H312+H332, H315, H319, H335
References & Citations
[1]Ozawa-Umeta H, et, al. Curcumin β-D-glucuronide exhibits anti-tumor effects on oxaliplatin-resistant colon cancer with less toxicity in vivo. Cancer Sci. 2020 May;111 (5) :1785-1793.|[2]Ozawa H, et, al. Curcumin β-D-Glucuronide Plays an Important Role to Keep High Levels of Free-Form Curcumin in the Blood. Biol Pharm Bull. 2017;40 (9) :1515-1524.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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