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ISR-IN-1

ISR-IN-1 (Compound 48) is an inhibitor of the integrated stress response (EC50: 0.6 nM) [1].

Product Specifications

CAS Number

1628478-15-8

UNSPSC

12352005

Hazard Statement

H302

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/isr-in-1.html

Purity

98.92

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

FC(C=C1OCC(N[C@H](CC2)CC[C@@H]2NC(COC3=CC(F)=C(C=C3)Cl)=O)=O)=C(C=C1)Cl

Molecular Formula

C22H22Cl2F2N2O4

Molecular Weight

487.32

Precautions

H302

References & Citations

[1]Hearn BR, et al. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19;11 (8) :870-80.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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