SAAP 148 (TFA)
SAAP 148 TFA is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC50 of 0.8-12.8 μM[1].
Product Specifications
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/saap-148-tfa.html
Purity
99.72
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(C)N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N2[C@H](CCC2)C(N[C@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)C(C)C)=O)=O)CCCCN)=O)CCCCN)=O)CC(C)C)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CC3=CNC4=C3C=CC=C4)=O)CC5=CC=C(O)C=C5)=O)CCCNC(N)=N)=O)CCCCN)=O)CC(C)C)=O)CC(C)C)=O)CCCCN)=O)=O)C(C)C)=O)CCCNC(N)=N)=O)CCCCN)=O)CC6=CNC7=C6C=CC=C7)=O)C(C)C)=O)CCCNC(N)=N)=O)CCCCN)=O)CC(C)C.OC(C(F)(F)F)=O.[x]
Molecular Formula
C157H261N49O27.xC2HF3O2
Molecular Weight
3267.06 (free base)
References & Citations
[1]de Breij A, et al., The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms. Sci Transl Med. 2018 Jan 10;10 (423) :eaan4044.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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