BAR-2227
BAR-2227 (compound 3a) is a FXR agonist and LIFR inhibitor. BAR-2227 can be used to study liver fibrosis and inflammation[1].
Product Specifications
CAS Number
[2409154-23-8]
UNSPSC
12352005
Target
FXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bar-2227.html
Smiles
CC1=C(C(C2=C(C=CC=C2Cl)Cl)=NO1)COC3=CC=C(C=C3)C4=CC(C(O)=O)=CC=C4
Molecular Formula
C24H17Cl2NO4
Molecular Weight
454.30
References & Citations
[1]Rapacciuolo P, et al. Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis. J Med Chem. 2024 Oct 9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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