Human Recombinant MMP-9

<strong>Human Recombinant MMP-9 </strong>_x000D_ <strong>Catalog number:</strong> B2011457_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 40 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80 °C_x000D_ <strong>Keywords:</strong> Matrix metalloproteinases 9, MMP-9 (Catalytic Domain), human recombinant_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Dong H, Diao H, Zhao Y, Xu H, Pei S, Gao J, Wang J, Hussain T, Zhao D, Zhou X, Lin D. Overexpression of matrix metalloproteinase-9 in breast cancer cell lines remarkably increases the cell malignancy largely via activation of transforming growth factor beta/SMAD signalling Cell Prolif. 2019 Sep;52(5):e12633._x000D_ 2: Jeong HJ, Kim EJ, Kim JK, Kim YG, Lee CS, Ko BJ, Kim BG. Expression of soluble recombinant human matrix metalloproteinase 9 and generation of its monoclonal antibody Protein Expr Purif. 2021 Nov;187:105931._x000D_ 3: Kim ML, Sung KR, Kwon J, Shin JA. Statins Suppress TGF-β2-Mediated MMP-2 and MMP-9 Expression and Activation Through RhoA/ROCK Inhibition in Astrocytes of the Human Optic Nerve Head Invest Ophthalmol Vis Sci. 2020 May 11;61(5):29._x000D_ 4: Golab P, Kielbus M, Bielewicz J, Kurzepa J. The effect of recombinant tissue plasminogen activator on MMP-2 and MMP-9 activities in vitro Neurol Res. 2015 Jan;37(1):9-13._x000D_ 5: Rossano R, Larocca M, Riviello L, Coniglio MG, Vandooren J, Liuzzi GM, Opdenakker G, Riccio P. Heterogeneity of serum gelatinases MMP-2 and MMP-9 isoforms and charge variants J Cell Mol Med. 2014 Feb;18(2):242-52._x000D_ 6: Xue M, McKelvey K, Shen K, Minhas N, March L, Park SY, Jackson CJ. Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation Rheumatology (Oxford). 2014 Dec;53(12):2270-9._x000D_ 7: Ardi VC, Kupriyanova TA, Deryugina EI, Quigley JP. Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20262-7._x000D_ 8: Kurisaka C, Oku T, Itoh S, Tsuji T. Role of sialic acid-containing glycans of matrix metalloproteinase-9 (MMP-9) in the interaction between MMP-9 and staphylococcal superantigen-like protein 5 Microbiol Immunol. 2018 Mar;62(3):168-175._x000D_ 9: Kim YH, Kwon HJ, Kim DS. Matrix metalloproteinase 9 (MMP-9)-dependent processing of βig-h3 protein regulates cell migration, invasion, and adhesion J Biol Chem. 2012 Nov 9;287(46):38957-69._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30422384">10: Boon L, Ugarte-Berzal E, Martens E, Vandooren J, Rybakin V, Colau D, Gordon-Alonso M, van der Bruggen P, Stöcker W, Becker-Pauly C, Witters P, Morava E, Jaeken J, Proost P, Opdenakker G. Propeptide glycosylation and galectin-3 binding decrease proteolytic activation of human proMMP-9/progelatinase B FEBS J. 2019 Mar;286(5):930-945. </a>_x000D_ _x000D_ <strong>Products Related to Human Recombinant MMP-9 can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>