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LRRC15, Cynomolgus/Rhesus macaque (HEK293, His)

LRRC15 is a cell membrane-expressed protein belonging to the LRR superfamily. Involved in cell-cell and cell-ECM interactions. The LRRC15 protein regulates the infectivity of SARS-CoV-2 by interacting with its spike protein. LRRC15 activates the β1-integrin /FAK signaling pathway to promote ovarian cancer metastasis. LRRC15 Protein, Cynomolgus/Rhesus macaque (HEK293, His) is the recombinant cynomolgus-derived LRRC15 protein, expressed by HEK293 , with C-His labeled tag.

Product Specifications

Product Name Alternative

LRRC15 Protein, Cynomolgus/Rhesus macaque (HEK293, His), Rhesus Macaque; Cynomolgus, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/lrrc15-protein-cynomolgus-hek293-his.html

Molecular Formula

102144360/707574 (Gene_ID) A0A2K5UKB6/F7FSB9 (Y22-G538) (Accession)

Molecular Weight

Approximately 70-80 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]Ray U, et al. Exploiting LRRC15 as a Novel Therapeutic Target in Cancer. Cancer Res. 2022 May 3;82 (9) :1675-1681.|[2]Berkowitz RL, et al. The Elusive Coreceptors for the SARS-CoV-2 Spike Protein. Viruses. 2022 Dec 25;15 (1) :67.|[3]Ray U, et al. Targeting LRRC15 Inhibits Metastatic Dissemination of Ovarian Cancer. Cancer Res. 2022 Mar 15;82 (6) :1038-1054.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Scientific Category

Recombinant Proteins

Frequently Asked Questions

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