SMURF2 Active Human

<strong>SMURF2 Active Human</strong>_x000D_ <strong>Catalog number:</strong> B2019706_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 72 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −70°C_x000D_ <strong>Keywords:</strong> E3 ubiquitin ligase SMURF2, MGC138150, SMAD specific E3 ubiquitin protein ligase 2_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Pi Y, Feng Q, Sun F, Wang Z, Zhao Y, Chen D, Liu Y, Lou G. Loss of SMURF2 expression enhances RACK1 stability and promotes ovarian cancer progression Cell Death Differ. 2023 Nov;30(11):2382-2392._x000D_ 2: Ni C, Chen Y, Xu Y, Zhao J, Li Q, Xiao C, Wu Y, Wang J, Wang Y, Zhong Z, Zhang L, Wu R, Liu Q, Wu X, Ke C, Zhu W, Chen J, Huang J, Wang Y, Wang J, Hu X. Flavin Containing Monooxygenase 2 Prevents Cardiac Fibrosis via CYP2J3-SMURF2 Axis Circ Res. 2022 Jul 5:101161CIRCRESAHA122320538._x000D_ 3: Kong D, Zhang Z, Chen L, Huang W, Zhang F, Wang L, Wang Y, Cao P, Zheng S. Curcumin blunts epithelial-mesenchymal transition of hepatocytes to alleviate hepatic fibrosis through regulating oxidative stress and autophagy Redox Biol. 2020 Sep;36:101600._x000D_ 4: Hiraiwa M, Fukasawa K, Iezaki T, Sabit H, Horie T, Tokumura K, Iwahashi S, Murata M, Kobayashi M, Suzuki A, Park G, Kaneda K, Todo T, Hirao A, Nakada M, Hinoi E. SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability Commun Biol. 2022 Jan 11;5(1):22._x000D_ 5: Shu Y, Jin X, Ji M, Zhang Z, Wang X, Liang H, Lu S, Dong S, Lin Y, Guo Y, Zhuang Q, Wang Y, Lei Z, Guo L, Meng X, Zhou G, Zhang W, Chang L. Ku70 Binding to YAP Alters PARP1 Ubiquitination to Regulate Genome Stability and Tumorigenesis Cancer Res. 2024 Sep 4;84(17):2836-2855._x000D_ 6: Lin Z, He H, Wang M, Liang J. MicroRNA-130a controls bone marrow mesenchymal stem cell differentiation towards the osteoblastic and adipogenic fate Cell Prolif. 2019 Nov;52(6):e12688._x000D_ 7: Tessier TM, Chowdhury A, Stekel Z, Fux J, Sartori MA, Teyra J, Jarvik N, Chung J, Kurinov I, Sicheri F, Sidhu SS, Singer AU, Zhang W. Structural and functional validation of a highly specific Smurf2 inhibitor Protein Sci. 2024 Feb;33(2):e4885._x000D_ 8: Manikoth Ayyathan D, Levy-Cohen G, Shubely M, Boutros-Suleiman S, Lepechkin-Zilbermintz V, Shokhen M, Albeck A, Gruzman A, Blank M. Development and characterisation of SMURF2-targeting modifiers J Enzyme Inhib Med Chem. 2021 Dec;36(1):401-409._x000D_ 9: Fu L, Cui CP, Zhang X, Zhang L. The functions and regulation of Smurfs in cancers Semin Cancer Biol. 2020 Dec;67(Pt 2):102-116._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31003445">10: Emanuelli A, Manikoth Ayyathan D, Koganti P, Shah PA, Apel-Sarid L, Paolini B, Detroja R, Frenkel-Morgenstern M, Blank M. Altered Expression and Localization of Tumor Suppressive E3 Ubiquitin Ligase SMURF2 in Human Prostate and Breast Cancer Cancers (Basel). 2019 Apr 18;11(4):556. </a>_x000D_ _x000D_ <strong>Products Related to SMURF2 Active Human can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>