PA-9
Product Specifications
UNSPSC Description
PA-9 is a pituitary adenylate cyclase-activating polypeptide (PACAP) type I (PAC1) receptor antagonist. PA-9 dose dependently inhibits PACAP-induced cAMP elevation with an IC50 of 5.6 nM. PA-9 can be used for the research of neuropathic and/or inflammatory pain[1].
Target Antigen
PACAP Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pa-9.html
Purity
99.73
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C(C1)CN(C2=NNC3=C2C=CC=C3)C1=O)NCCC4=CN=CN4
Molecular Weight
338.36
References & Citations
[1]Takasaki I, et al. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor. J Pharmacol Exp Ther. 2018 Apr;365(1):1-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-129421/PA-9-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-129421/PA-9-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1436004-46-4
Available Sizes
Curated Selection
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