4-Methylumbelliferyl-β-D-glucuronide hydrate

4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λex=362 nm, λem=445 nm) . 4-Methylumbelliferyl-β-D-glucuronide hydrate has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli[1][2][3].

Product Specifications

CAS Number

[881005-91-0]

Product Name Alternative

MUG

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye; β-glucuronidase

Type

Dye Reagents

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/4-Methylumbelliferyl-_beta_-D-glucuronide_hydrate.html

Purity

99.92

Solubility

DMSO : 150 mg/mL (ultrasonic) |H2O : 5.2 mg/mL (ultrasonic; warming)

Smiles

O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=CC=C(C(O3)=C2)C(C)=CC3=O.O

Molecular Formula

C16H18O10

Molecular Weight

370.31

Precautions

H302, H315, H319, H335

References & Citations

[1]George I, et al. Use of beta-D-galactosidase and beta-D-glucuronidase activities for quantitative detection of totaland fecal coliforms in wastewater. Can J Microbiol. 2001 Jul;47 (7) :670-5.|[2]Sperker B, et al. High-performance liquid chromatographic quantification of 4-methylumbelliferyl-beta-D-glucuronide as a probe for human beta-glucuronidase activity in tissue homogenates. J Chromatogr B Biomed Appl. 1996 Oct 11;685 (1) :181-4. |[3]Villari P, et al. An evaluation of the use of 4-methylumbelliferyl-beta-D-glucuronide (MUG) in different solid media for the detection and enumeration of Escherichia coli in foods. Lett Appl Microbiol. 1997 Apr;24 (4) :286-90.