Eflapegrastim
Eflapegrastim is a composite protein consisting of a genetically modified granulocyte-colony stimulating factor (GCSF) molecule linked via a chemical bond to an IgG4 Fc fragment (LAPS-carrier) . Eflapegrastim targets to G-CSF receptor (c-Fms) . Eflapegrastim stimulates proliferation and differentiation of neutrophil progenitor cells and maintains stable numbers of mature and functional neutrophils. Eflapegrastim also shortens the duration of neutropenia[1].
Product Specifications
CAS Number
1384099-30-2
UNSPSC
12352203
Target
C-Fms
Type
Inhibitory Antibodies
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/eflapegrastim.html
Solubility
10 mM in DMSO
Smiles
[Eflapegrastim]
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched
Frequently Asked Questions
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