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Uroguanylin (human)

Uroguanylin (human) is a natural ligand for the Guanylyl Cyclase (GCC) receptor expressed in metastatic colorectal cancer tumors. Uroguanylin (human) has anti-tumor actions in an animal model for human colon cancer[1][2].

Product Specifications

CAS Number

[154525-25-4]

UNSPSC

12352209

Target

Guanylate Cyclase

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/uroguanylin-human.html

Purity

98.35

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H]([C@H](O)C)C(NC1)=O)=O)NC2=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC(C)C)C(O)=O)=O)NC1=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@H]2C)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(N)=O)N

Molecular Formula

C64H102N18O26S4

Molecular Weight

1667.86

References & Citations

[1]Lewis DK, et al. Hypertrehalosemic hormone in a cockroach: molecular cloning and expression. Mol Cell Endocrinol. 1997;130 (1-2) :101-108.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

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Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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