PD 169316
PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor, with IC50 of 89 nM. PD169316 selectively inhibits the kinase activity of the phosphorylated p38 without hindering upstream kinases to phosphorylate p38. PD169316 shows antiviral activity against Enterovirus71. PD169316 shows antiviral activity against Enterovirus71.
Product Specifications
CAS Number
152121-53-4
UNSPSC
12352005
Hazard Statement
H301, H315, H318, H335
Target
Autophagy; Enterovirus; p38 MAPK
Type
Reference compound
Related Pathways
Anti-infection; Autophagy; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd-169316.html
Purity
98.60
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
FC(C=C1)=CC=C1C2=C(C3=CC=NC=C3)NC(C4=CC=C([N+]([O-])=O)C=C4)=N2
Molecular Formula
C20H13FN4O2
Molecular Weight
360.34
Precautions
H301, H315, H318, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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