4BP-TQS
4BP-TQS is a potent allosteric agonist of α7 nAChR. 4BP-TQS activates nAChRs via an allosteric transmembrane site[1].
Product Specifications
CAS Number
[360791-49-7]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/4bp-tqs.html
Purity
99.89
Solubility
DMSO : 250 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(N)(C1=CC=C2NC(C3CC=CC3C2=C1)C4=CC=C(C=C4)Br)=O
Molecular Formula
C18H17BrN2O2S
Molecular Weight
405.31
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Gill JK, et al. Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc Natl Acad Sci U S A. 2011;108 (14) :5867-5872.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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