Trimethylamine-N-oxide-13C3
Trimethylamine-N-oxide-13C3 is the 13C-labeled Trimethylamine N-oxide. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway[1][2][3].
Product Specifications
UNSPSC
12352211
Target
Endogenous Metabolite; Isotope-Labeled Compounds; NOD-like Receptor (NLR) ; Reactive Oxygen Species (ROS) ; TGF-beta/Smad
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others; Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/trimethylamine-n-oxide-13c3.html
Solubility
10 mM in DMSO
Smiles
[13CH3][N+]([13CH3])([O-])[13CH3]
Molecular Formula
13C3H9NO
Molecular Weight
78.09
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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