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Propargyl-PEG3-amine

Product Specifications

UNSPSC Description

Propargyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/propargyl-peg3-amine.html

Solubility

10 mM in DMSO

Smiles

C#CCOCCOCCOCCN

Molecular Weight

187.24

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-140033/Propargyl-PEG3-amine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-140033/Propargyl-PEG3-amine-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

932741-19-0

Available Sizes

Curated Selection

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