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Dibromomaleimide-C5-COOH

Dibromomaleimide-C5-COOH (DBM-C5-COOH) is a bifunctional dibromomaleimide (DBM) linker. Dibromomaleimide-C5-COOH can be used to connect MMAF and to synthesize ADC[1].

Product Specifications

CAS Number

1443214-97-8

Product Name Alternative

DBM-C5-COOH

UNSPSC

12352203

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dibromomaleimide-c5-cooh.html

Purity

99.40

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(CCCCCN1C(C(Br)=C(C1=O)Br)=O)O

Molecular Formula

C10H11Br2NO4

Molecular Weight

369.01

References & Citations

[1]Behrens CR, et al. Antibody-Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs. Mol Pharm. 2015 Nov 2;12 (11) :3986-98.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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