L 694746
L 694746 is the metabolite of L-689502. L 694746 is an inhibitor for HIV-1 protease with an IC50 of 1 nM and a Ki of 0.34 nM[1].
Product Specifications
CAS Number
139934-80-8
UNSPSC
12352005
Target
HIV; HIV Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/l-694746.html
Smiles
O=C(O)COC1=CC=C(C[C@@H](C(N[C@@H]2[C@H](O)CC3=C2C=CC=C3)=O)C[C@H](O)[C@@H](NC(OC(C)(C)C)=O)CC4=CC=CC=C4)C=C1
Molecular Formula
C35H42N2O8
Molecular Weight
618.72
References & Citations
[1]Lingham RB, et al. HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502. Biochem Biophys Res Commun. 1991 Dec 31;181 (3) :1456-61.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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