Levomefolate-13C5 (calcium)

Levomefolate-13C5 (calcium) is the 13C-labeled Levomefolate (calcium) . Levomefolate calcium is an artificial form of folate.

Product Specifications

UNSPSC

12352005

Target

Antifolate; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/levomefolate-13c5-calcium.html

Solubility

10 mM in DMSO

Smiles

O=[13C]([O-])[13C][13C][13C@@]([13C]([O-])=O)NC(C1=CC=C(NC[C@@H]2N(C)C3=C(N=C(N)NC3=O)NC2)C=C1)=O.[Ca+2]

Molecular Formula

C15 13C5H18CaN7O6

Molecular Weight

497.44

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Fruzzetti F. Beyaz?: an oral contraceptive fortified with folate. Womens Health (Lond Engl) . 2012 Jan;8 (1) :13-9.|[3]Wiesinger H, Eydeler U, Richard F, et al. Bioequivalence evaluation of a folate-supplemented oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium versus ethinylestradiol/drospirenone and levomefolate calcium alone. Clin Drug Investig. 2012 Oct 1;32 (10) :673-84.|[4]Hartmut Blodea, Christine Klippingb, Frank Richardc, et al. Bioequivalence study of an oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium relative to ethinylestradiol/drospirenone and to levomefolate calcium alone. Contraception.2012, 85 (2), :177-184|[5]Rapkin RB, Creinin MD. The combined oral contraceptive pill containing drospirenone and ethinyl estradiol plus levomefolate calcium. Expert Opin Pharmacother. 2011 Oct;12 (15) :2403-10. doi: 10.1517/14656566.2011.610791.|[6]Levomefolic_acid