PB131
Product Specifications
UNSPSC Description
PB131 is a selective and brain-permeable HDAC6 inhibitor with high binding affinity (IC50: 1.8 nM). PB131 has potent anti-inflammatory activity. PB131 can be used for research of inflammation, especially neuroinflammation[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pb131.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(F)=C(C=C1)CN2CCCC3=CC=CN=C32)NO
Molecular Weight
301.32
References & Citations
[1]Liu G, et al. Design, synthesis, and anti-inflammatory activity characterization of novel brain-permeable HDAC6 inhibitors. Eur J Med Chem. 2023 Jun 5;254:115327.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149966/PB131-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149966/PB131-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2924425-63-6
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
RC220006L1V 200 µL
VPS24 (CHMP3) (NM_016079) Human Tagged ORF Clone Lentiviral Particle
Ask
View Details 
MBS1487961-01 0.02 mg (E-Coli)
Recombinant Moorella thermoacetica Dihydrodipicolinate synthase (dapA)
Ask
View Details 
MBS1487961-02 0.02 mg (Yeast)
Recombinant Moorella thermoacetica Dihydrodipicolinate synthase (dapA)
Ask
View Details MBS1487961-03 0.1 mg (E-Coli)
Recombinant Moorella thermoacetica Dihydrodipicolinate synthase (dapA)
Ask
View Details MBS1487961-04 0.1 mg (Yeast)
Recombinant Moorella thermoacetica Dihydrodipicolinate synthase (dapA)
Ask
View Details