BMS-986124
BMS-986124 is a μ-opioid receptor silent allosteric modulator (μ-SAMs) . BMS-986124 antagonizes positive allosteric modulator effect of BMS-986122 (µ-OR PAM) [1].
Product Specifications
CAS Number
[1447968-71-9]
UNSPSC
12352005
Hazard Statement
H319
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bms-986124.html
Purity
99.00
Smiles
O=S(C1=CC=C(C=C1)Cl)(N2CCSC2C3=CC=C(C=C3OC)Br)=O
Molecular Formula
C16H15BrClNO3S2
Molecular Weight
448.78
Precautions
H319
References & Citations
[1]Burford NT, et al. Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor. Proc Natl Acad Sci U S A. 2013 Jun 25;110 (26) :10830-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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