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T-Boc-Aminooxy-PEG5-azide

T-Boc-Aminooxy-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. t-Boc-Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

2250216-95-4

UNSPSC

12352211

Hazard Statement

H240

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/t-boc-aminooxy-peg5-azide.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)NOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Molecular Formula

C17H34N4O8

Molecular Weight

422.47

Precautions

P210-P234-P235-P240-P280-P370+P372+P380+P373-P403-P410-P420-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; PEG Linkers

Available Sizes

Frequently Asked Questions

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