Keap1-Nrf2 probe

Keap1-Nrf2 probe is a Keap1-Nrf2 probe[1].

Product Specifications

CAS Number

[2430031-36-8]

UNSPSC

12352209

Target

Keap1-Nrf2

Type

Peptides

Related Pathways

NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/keap1-nrf2-probe.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)C

Molecular Formula

C48H72N10O19

Molecular Weight

1093.14

References & Citations

[1]Jiang ZY, et al. Discovery of potent Keap1-Nrf2 protein-protein interaction inhibitor based on molecular binding determinants analysis. J Med Chem. 2014 Mar 27;57 (6) :2736-45..