Bupropion morpholinol-d6

Bupropion morpholinol-d6 is the deuterated form of Bupropion morpholinol. Bupropion morpholinol is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities[1].

Product Specifications

CAS Number

[1216893-18-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Dopamine Transporter; Isotope-Labeled Compounds; nAChR

Type

Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

99.28

Solubility

10 mM in DMSO

Smiles

OC1(C2=CC=CC(Cl)=C2)C(C)NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])CO1

Molecular Formula

C13H12D6ClNO2

Molecular Weight

261.78

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhu A Z X, et al. CYP2B6 and bupropion's smoking‐cessation pharmacology: the role of hydroxybupropion[J]. Clinical Pharmacology & Therapeutics, 2012, 92 (6) : 771-777.