Shz-1

Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells[1].

Product Specifications

CAS Number

[326886-05-9]

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/shz-1.html

Purity

99.88

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=CC=C1)(N/N=C/C2=CC(Br)=CC=C2O)=O

Molecular Formula

C13H11BrN2O3S

Molecular Weight

355.21

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Changlong Nan, et al. Expression of sarcomeric tropomyosin in striated muscles in axolotl treated with shz-1, a small cardiogenic molecule. Cardiovasc Toxicol. 2015 Jan;15 (1) :29-40.