Shz-1
Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells[1].
Product Specifications
CAS Number
326886-05-9
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/shz-1.html
Purity
99.88
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=CC=C1)(N/N=C/C2=CC(Br)=CC=C2O)=O
Molecular Formula
C13H11BrN2O3S
Molecular Weight
355.21
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Changlong Nan, et al. Expression of sarcomeric tropomyosin in striated muscles in axolotl treated with shz-1, a small cardiogenic molecule. Cardiovasc Toxicol. 2015 Jan;15 (1) :29-40.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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