Macrophage Colony-Stimulating Factor (Human)

<strong>Macrophage Colony-stimulating Factor (Human)</strong>_x000D_ <strong>Catalog number:</strong> B2010318_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Macrophage Colony-stimulating Factor (Human) expressed in CHO. This protein acts as a hematopoietic growth factor with various glycosylation sites that affects the survival and function of macrophages._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuM-CSF; CSF-1; MGI-IM_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Ushach I, Zlotnik A. Biological role of granulocyte macrophage colony-_x000D_ stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) on_x000D_ cells of the myeloid lineage. J Leukoc Biol. 2016 Sep;100(3):481-9._x000D_ _x000D_ 2: Jin X, Kruth HS. Culture of Macrophage Colony-stimulating Factor_x000D_ Differentiated Human Monocyte-derived Macrophages. J Vis Exp. 2016 Jun_x000D_ 30;(112):54244._x000D_ _x000D_ 3: Hume DA, MacDonald KP. Therapeutic applications of macrophage colony-_x000D_ stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R)_x000D_ signaling. Blood. 2012 Feb 23;119(8):1810-20._x000D_ _x000D_ 4: Chockalingam S, Ghosh SS. Macrophage colony stimulating factor and cancer: a_x000D_ review. Tumour Biol. 2014 Nov;35(11):10635-44._x000D_ _x000D_ 5: Hua F, Tian Y, Gao Y, Li C, Liu X. Colony‑stimulating factor 1 receptor_x000D_ inhibition blocks macrophage infiltration and endometrial cancer cell_x000D_ proliferation. Mol Med Rep. 2019 Apr;19(4):3139-3147._x000D_ _x000D_ 6: Yang X, Pande S, Scott C, Friesel R. Macrophage colony stimulating factor_x000D_ pretreatment of bone marrow progenitor cells regulates osteoclast_x000D_ differentiation based upon the stage of myeloid development. J Cell Biochem._x000D_ 2019 Aug;120(8):12450-12460._x000D_ _x000D_ 7: Kumari A, Silakari O, Singh RK. Recent advances in colony stimulating_x000D_ factor-1 receptor/c-FMS as an emerging target for various therapeutic_x000D_ implications. Biomed Pharmacother. 2018 Jul;103:662-679._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30767584/">8: Liu C, Sun W, Zhuo G, Zhang Z. Impacts of macrophage colony-stimulating_x000D_ factor (M-CSF) on the expression of natriuretic peptide precursor type C (NPPC)_x000D_ and regulation of meiotic resumption. Gynecol Endocrinol. 2019_x000D_ Apr;35(4):320-323. </a>_x000D_ _x000D_ <strong>Products Related to Macrophage Colony-stimulating Factor (Human) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>