α-Conotoxin LtIA
Product Specifications
UNSPSC Description
α-Conotoxin LtIA is an α3β2 nAChR blocker (IC50=9.8 nM), that can be obtained from Conus litteratus venom. Alpha-Conotoxin LtIA can be used in the study of neurological diseases (such as Parkinson's disease, pain)[1].
Target Antigen
nAChR
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H]1C(N[C@H](C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@@H](C)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@H]3CC(C)C)=O)=O)=O)=O)=O)=O)=O)CSSC1)=O)C)=O)=O)=O)=O)CSSC[C@@H](C(N)=O)NC3=O)=O)CN
Molecular Weight
1600.87
References & Citations
[1]Luo S, et al. Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the alpha3beta2 nicotinic receptor. J Biol Chem. 2010 Apr 16;285(16):12355-66.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
QP6400-ec-1mg 1mg
Recombinant Human Myosin light chain 1/ 3, skeletal muscle isoform Protein, GST, E.coli-1mg
Ask
View Details NBP2-72505FR 0.1 mL
Mouse Monoclonal beta II Tubulin B Antibody (OTI6D11) [DyLight 680]
Ask
View Details