Polyadenylic acid (potassium)
Polyadenylic acid potassium, also known as Poly (A), is enzymatically added to messenger RNA (mRNA) in eukaryotic cells to stabilize mRNAs. Poly (A) is used to evaluate binding on cationic liposomes doped with non-ionic nucleolipids. Poly (A) is used in small molecule mRNA targeted drug development to evaluate the binding of potential therapeutic agents such as the Isoquinoline group of alkaloids. Small molecules that could bind to this poly (A) tail could influence and possibly inhibit mRNA function and subsequent protein production in the cell leading to the development of new type of therapeutic agents.
Product Specifications
CAS Number
26763-19-9
Product Name Alternative
Poly (A)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/polyadenylic-acid-potassium.html
Purity
90.00
Smiles
NC1=C2C(N([C@@H]3O[C@H](COP(O)(O[K])=O)[C@@H](O)[C@H]3O)C=N2)=NC=N1.[n]
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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