Neoxanthin
Neoxanthin is a major xanthophyll carotenoid and a precursor of the plant hormone abscisic acid in dark green leafy vegetables. Neoxanthin is a potent antioxidant and light-harvesting pigment. Neoxanthin induces apoptosis and has anticancer actions[1][2].
Product Specifications
CAS Number
14660-91-4
UNSPSC
12352005
Target
Apoptosis; DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/neoxanthin.html
Concentration
1.25 μM * 127 μL in Ethanol
Purity
97.0
Solubility
10 mM in DMSO
Smiles
CC(/C=C/[C@](O1)(C(C)(C2)C)[C@]1(C[C@H]2O)C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=[C@@]=C([C@](O)(C3)C)C(C)(C[C@@H]3O)C
Molecular Formula
C40H56O4
Molecular Weight
600.87
References & Citations
[1]E Kotake-Nara, et al. Carotenoids Affect Proliferation of Human Prostate Cancer Cells. J Nutr. 2001 Dec;131 (12) :3303-6.|[2]Ramesh Kumar Saini, et al. An Efficient One-Step Scheme for the Purification of Major Xanthophyll Carotenoids From Lettuce, and Assessment of Their Comparative Anticancer Potential. Food Chem. 2018 Nov 15;266:56-65.|[3]Akira Asai, et al. An Epoxide-Furanoid Rearrangement of Spinach Neoxanthin Occurs in the Gastrointestinal Tract of Mice and in Vitro: Formation and Cytostatic Activity of Neochrome Stereoisomers. J Nutr. 2004 Sep;134 (9) :2237-43.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, protect from light, 2 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
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