Triglycidyl isocyanurate (Standard)

Triglycidyl isocyanurate (Standard) is the analytical standard of Triglycidyl isocyanurate. This product is intended for research and analytical applications. Triglycidyl isocyanurate (TGIC; Teroxirone) is a triazene triepoxide with antiangiogenic and antineoplastic activities. Triglycidyl isocyanurate inhibits the growth of non-small-cell-lung cancer cells via?p53 activation. Triglycidyl isocyanurate induces cell apoptosis. Triglycidyl isocyanurate can be used for cancer research[1][2].

Product Specifications

CAS Number

[2451-62-9]

Product Name Alternative

TGIC (Standard)

UNSPSC

12352005

Target

Apoptosis; MDM-2/p53; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Others

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/triglycidyl-isocyanurate-standard.html

Smiles

O=C(N(C1=O)CC2CO2)N(C(N1CC3CO3)=O)CC4CO4

Molecular Formula

C12H15N3O6

Molecular Weight

297.26

References & Citations

[1]Yu-Ling Ni, et al. Teroxirone motivates apoptotic death in tumorspheres of human lung cancer cells. Chem Biol Interact. 2018 Aug 1;291:137-143|[2]Seung-Hun Kim, et al. Teroxirone suppresses growth and motility of human hepatocellular carcinoma cells.Biomed Pharmacother. 2018 Mar;99:997-1008