IRF3, Mouse (P.pastoris, Myc, His)

The IRF3 protein is an important transcriptional regulator that coordinates type I interferon-dependent immune responses against DNA and RNA viruses. In uninfected cells, it remains inactive, but viral infection triggers phosphorylation of IKBKE and TBK1 kinases, leading to conformational changes. IRF3 Protein, Mouse (P.pastoris, Myc, His) is the recombinant mouse-derived IRF3 protein, expressed by P. pastoris , with C-Myc, N-10*His labeled tag.