L-651392
L-651392 is an orally active and specific 5-lipoxygenase inhibitor that inhibits the production of leukotrienes. L-651392 controls the inflammatory process in Escherichia coli pyelonephritis by preventing inflammatory cells from reaching the site of infection and protecting the renal tubules from inflammation-related damage during pyelonephritis[1].
Product Specifications
CAS Number
93211-49-5
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/l-651392.html
Smiles
O=C1C(Br)=C2SC3=C(N=C2C=C1OC)C=CC(OC)=C3
Molecular Formula
C14H10BrNO3S
Molecular Weight
352.20
References & Citations
[1]Tardif M, et al. L-651,392, a potent leukotriene inhibitor, controls inflammatory process in Escherichia coli pyelonephritis[J]. Antimicrobial agents and chemotherapy, 1994, 38 (7) : 1555-1560.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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