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L-651392

L-651392 is an orally active and specific 5-lipoxygenase inhibitor that inhibits the production of leukotrienes. L-651392 controls the inflammatory process in Escherichia coli pyelonephritis by preventing inflammatory cells from reaching the site of infection and protecting the renal tubules from inflammation-related damage during pyelonephritis[1].

Product Specifications

CAS Number

93211-49-5

UNSPSC

12352005

Target

Lipoxygenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/l-651392.html

Smiles

O=C1C(Br)=C2SC3=C(N=C2C=C1OC)C=CC(OC)=C3

Molecular Formula

C14H10BrNO3S

Molecular Weight

352.20

References & Citations

[1]Tardif M, et al. L-651,392, a potent leukotriene inhibitor, controls inflammatory process in Escherichia coli pyelonephritis[J]. Antimicrobial agents and chemotherapy, 1994, 38 (7) : 1555-1560.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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